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PROLINE-PROMOTED DEHYDROXYLATION OF A-KETOLS

Mostinski, Y., Lankri, D., Konovalov. Y., Nataf, R., Tsvelikhovsky, D.

Chem. Sci, 2019, DOI: 10.1039/C9SC02543J.

METHYLENE-CYCLOALKYLACETATE (MCA) SCAFFOLD-BASED COMPOUNDS AS NOVEL NEUROTROPIC AGENTS

Lankri, D., Haham, D., Lahiani, A., Lazarovici, P., Tsvelikhovsky, D.

ACS Chem. Neurosci. 2018, 9 (4), 691-698.

METHYLENE-CYCLOALKYLACETATE (MCA) SCAFFOLD-BASED COMPOUNDS AS NOVEL NEUROTROPIC AGENTS

Lankri, D., Haham, D., Lahiani, A., Lazarovici, P., Tsvelikhovsky, D.

ACS Chem. Neurosci. 2018, 9 (4), 691-698.

PALLADIUM-CATALYZED CASCADE ASSEMBLY OF TRICYCLIC SPIROETHERS FROM DIENE-ALCOHOL PRECURSORS

Lankri, D. Mostinski, Y., Tsvelikhovsky‚ D.
J. Org. Chem. 2017, 82 (18), 9452-9463.

A MULTIFACETED ENAMINONE - ADAPTABLE BUILDING BLOCK FOR SYNTHESIS OF HETEROCYCLIC SCAFFOLDS THROUGH CONCEPTUALLY DISTINCT 1,2-, 1,3-, 1,4- AND C-O BOND FORMING ANNULATIONS

Lankri, D., Albarghouti, G., Mahameed, M., Tsvelikhovsky‚ D.
J. Org. Chem. 2017, 82 (14), 7101-7113.

TRICYCLIC SPIROLACTONES AS MODULAR TRPV1 SYNTHETIC AGONISTS

Mostinski, Y., Noy, G., Kumar, R., Tsvelikhovsky‚ D., Priel, A.
ACS Chem. Neurosci. 2017, 8 (8), 1688-1696.

TRANSITION METAL-CATALYZED SYNTHESIS OF SPIROLACTONES

Mostinski, Y., Lankri, D., Tsvelikhovsky‚ D.
SYNTHESIS Review 2017, 49(11), 2361-2373.

PALLADIUM-CATALYZED CYCLIZATION OF FREE HYDROXYALKENOIC ACIDS: REGIO- AND CHEMOSELECTIVE ACCESS TO METHYLENE LACTONES

Mostinski, Y., Kotikalapudi, R., Valerio, V., Nataf, R., Tsvelikhovsky‚ D.
Adv. Synth. Catal. 2017, 359, 1164-1169.

CASCADE PALLADIUM-CATALYZED WACKER LACTONIZATION-HECK REACTION: RAPID ASSEMBLY OF SPIRANOID LACTONES

Albarghouti, G., Kotikalapudi, R., Lankri, D., Valerio, V., Tsvelikhovsky‚ D.
Chem. Commun. 2016, 52, 3095-3098.

FRONT COVER

STEREO- AND REGIOSELECTIVE SYNTHESIS OF TRICYCLIC SPIROLACTONES VIA DIASTEREOMERIC DIFFERENTIATION OF A COLLECTIVE KEY PRECURSOR

Valerio, V., Mostinski, Y., Kotikalapudi, R., Tsvelikhovsky‚ D.
Chem. Eur. J. 2016, 22, 2640-2647.

HOT PAPER - FRONTISPIECE

SYNTHESIS OF TRICYCLIC SPIRANOID LACTONES VIA I2/SM(II)- AND I2/PALLADIUM-MEDIATED CYCLIZATIONS OF A COMMON CYCLOALKYLMETHYLENE PRECURSOR

Mostinski, Y., Valerio, V., Lankri, D., Tsvelikhovsky‚ D.
J. Org. Chem. 2015, 80 (21), 10464-10473

NEUROTHROPHIC ACTIVITY AND SAFETY OF METHYLENE-CYCLOALKYLACETATE (MCA) DERIVATIVES 3-(3-ALLYL-2-METHYLENECYCLOHEXYL)PROPANOIC ACID

LAHIANI, A., HAHAM-GEULA, D., LANKRI, D., CORNELL-KENNON, S., SCHAEFER, E. M., Tsvelikhovsky, D., LAZAROVICI, P.

ACS Chem. Neurosci. 2020, ASAP.

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TSVELIKHOVSKY RESEARCH GROUP

The Laboratory of Synthetic Medicinal Chemistry

PROLINE-PROMOTED DEHYDROXYLATION OF A-KETOLS

METHYLENE-CYCLOALKYLACETATE (MCA) SCAFFOLD-BASED COMPOUNDS AS NOVEL NEUROTROPIC AGENTS

METHYLENE-CYCLOALKYLACETATE (MCA) SCAFFOLD-BASED COMPOUNDS AS NOVEL NEUROTROPIC AGENTS

PALLADIUM-CATALYZED CASCADE ASSEMBLY OF TRICYCLIC SPIROETHERS FROM DIENE-ALCOHOL PRECURSORS

A MULTIFACETED ENAMINONE - ADAPTABLE BUILDING BLOCK FOR SYNTHESIS OF HETEROCYCLIC SCAFFOLDS THROUGH CONCEPTUALLY DISTINCT 1,2-, 1,3-, 1,4- AND C-O BOND FORMING ANNULATIONS

TRICYCLIC SPIROLACTONES AS MODULAR TRPV1 SYNTHETIC AGONISTS

TRANSITION METAL-CATALYZED SYNTHESIS OF SPIROLACTONES

PALLADIUM-CATALYZED CYCLIZATION OF FREE HYDROXYALKENOIC ACIDS: REGIO- AND CHEMOSELECTIVE ACCESS TO METHYLENE LACTONES

CASCADE PALLADIUM-CATALYZED WACKER LACTONIZATION-HECK REACTION: RAPID ASSEMBLY OF SPIRANOID LACTONES

STEREO- AND REGIOSELECTIVE SYNTHESIS OF TRICYCLIC SPIROLACTONES VIA DIASTEREOMERIC DIFFERENTIATION OF A COLLECTIVE KEY PRECURSOR

SYNTHESIS OF TRICYCLIC SPIRANOID LACTONES VIA I2/SM(II)- AND I2/PALLADIUM-MEDIATED CYCLIZATIONS OF A COMMON CYCLOALKYLMETHYLENE PRECURSOR

NEUROTHROPHIC ACTIVITY AND SAFETY OF METHYLENE-CYCLOALKYLACETATE (MCA) DERIVATIVES 3-(3-ALLYL-2-METHYLENECYCLOHEXYL)PROPANOIC ACID

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